Alcohols and polyols
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- (50)
- (31)
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- (1)
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- (1)
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- (1)
- (462)
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- (11)
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- (1)
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- (145)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
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- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
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- (2)
- (7)
- (12)
- (1)
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- (24)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Quinapril hydrochloride | 82586-55-8 | 98.3% | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Quinapril hydrochloride (CI-906) is a proagent in the angiotensin-converting enzyme (ACE) inhibitor class. It is used in the treatment of hypertension and congestive heart failure. Quinapril is rapidly de-esterified to quinaprilat, its active diacid metabolite, which is a potent ACE inhibitor.
- Potent angiotensin converting enzyme (ACE) inhibitor
- Used for hypertension and congestive heart failure treatment
- Rapidly de-esterified to active quinaprilat metabolite
- Appears as a white to off-white solid
- Store solid form at 4°C, sealed and away from moisture
- Store in solvent at -80°C for up to 6 months, or -20°C for 1 month, sealed and away from moisture
- High solubility in DMSO (≥ 100 mg/mL) and H2O (≥ 50 mg/mL)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.27% | 274.79 | 25 MG
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PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.
- Binds to the surface cavity and stabilizes Y220C (a p53 mutant)
- Kd of 167 μM (p53-Y220C)
- Relative binding affinity (Kd) of 150 μM in Ln229 cells
- Slows down its thermal denaturation rate
- Reduces the cell viability of engineered variants of Ln229 cells (125 μM, 48 hours)
- Enhances pro-apoptotic activity in all variants of Ln229 cells (p53wt, p53Y220C, p53G245S, p53R282W) when combined with NSC 123127 (1 μM)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Asenapine hydrochloride | 1412458-61-7 | 99.95% | 322.23 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Asenapine hydrochloride is an atypical antipsychotic that acts as an antagonist of serotonin, adreno, dopamine, and histamine receptors. It is utilized in research for schizophrenia and bipolar disorder.
- Acts as an antagonist of serotonin receptors (pKi: 8.4-10.5).
- Acts as an antagonist of adrenoceptors (pKi: 8.9-9.5).
- Acts as an antagonist of dopamine receptors (pKi: 8.9-9.4).
- Acts as an antagonist of histamine receptors (pKi: 8.2-9.0).
- Purity of 99.95%.
- Soluble in H2O (100 mg/mL) and DMSO (50 mg/mL).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | 99.8% | 1 ML
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Amiloride hydrochloride is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). It also acts as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is suitable for research applications targeting these pathways.
- Inhibitor of epithelial sodium channel (ENaC)
- Inhibitor of urokinase-type plasminogen activator receptor (uTPA)
- Blocker of polycystin-2 (PC2; TRPP2) channel
- Relatively selective ENaC inhibitor with IC50 ranging from 0.1 to 0.5 μM
- Demonstrated to reverse initial increases in collagen deposition in DOCA-salt hypertensive rats
- Delays the onset of proteinuria in stroke-prone spontaneously hypertensive rats (SHRSP)
- Antagonizes or prevents aldosterone actions in animal models of salt-dependent hypertension
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 100 MG
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SB-408124 Hydrochloride is a selective, non-peptide orexin receptor 1 (OX1) antagonist. It demonstrates high potency with Ki values of 57 nM in whole cells and 27 nM in membranes, exhibiting 50-fold selectivity over the OX2 receptor. This compound is for research use only.
- Potent OX1 receptor antagonist (Ki: 57 nM in whole cells, 27 nM in membranes)
- Exhibits 50-fold selectivity over OX2 receptor
- Attenuates orexin A-induced AVP mRNA levels in neuronal cultures
- Reduces anxiety and restores corticoliberin levels in vivo
- Demonstrates an anxiolytic effect
- Reduces mean arterial pressure in salt-sensitive rats
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Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 25 MG
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Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme. It is considered useful in the field of epigenetics and can serve as a starting point for new therapeutics targeting DNA methylation and gene transcription.
- Potent and selective inhibitor of TET enzyme
- IC50s of 33 μM for TET1 and 73 μM for TET2
- Significantly reduces global 5hmC levels in HT-22 cells
- Useful for epigenetics research
- Serves as a starting point for new therapeutics targeting DNA methylation and gene transcription
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Medchemexpress LLC Eperisone hydrochloride | 56839-43-1 | MFCD00941459 | 100.0% | 500 MG
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Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. It is a potent and selectively P2X7 receptor antagonist, and also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascular smooth muscles, demonstrating a variety of effects such as reduction of myotonia, improvement of circulation and suppression of the pain reflex.
- Orally active antispastic agent
- Vasodilator effect
- Used for research of muscle stiffness and pain
- Potent and selective P2X7 receptor antagonist
- Shows antagonism for human P2X3
- Relaxes both skeletal muscles and vascular smooth muscles
- Reduces myotonia
- Improves circulation
- Suppresses the pain reflex
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Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | MFCD04113213 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 1 ML
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Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide (CP-597396), a potent and selective inhibitor of the sodium-hydrogen exchanger type 1 (NHE-1). Supplied as a ready-to-use solution, it is intended for research applications targeting membrane transporter and ion-channel pathways.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Potent, selective NHE-1 inhibitor; reported IC50 ≈ 14 nM.
- High purity, typically ≥99.4% (HPLC).
- Molecular formula C17H19ClN6O2; molecular weight 374.82 g/mol.
- Soluble in DMSO (~20 mg/mL); may require warming or sonication.
- Store sealed, away from moisture; in solvent store -80°C for long term, -20°C for short term.
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Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 10 MM * 1 ML
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. It is a cardioselective beta-adrenergic receptor blocking agent.
- Functions as a selective beta1 adrenergic receptor blocker
- Cardioselective beta-adrenergic receptor blocking agent
- Applicable for research in hypertension
- Applicable for research in glaucoma
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Medchemexpress LLC W-7 isomer hydrochloride | 69762-85-2 | 99.7% | 377.33 g/mol | C16H22Cl2N2O2S | 5 MG
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W-7 isomer hydrochloride is the hydrochloride salt of an isomer of W-7, a selective calmodulin antagonist used in biochemical and cellular research to inhibit calmodulin-dependent signaling. Supplied as a powdered research reagent with specified purity and handling instructions, it is intended for laboratory research use only.
- Selective calmodulin antagonist for biochemical and cellular assays.
- High purity suitable for analytical and experimental applications.
- Supplied as a stable powder for convenient storage and handling.
- Available in small research quantities for assay development.
- Refer to safety data and handling instructions for proper use.
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Medchemexpress LLC Tandutinib hydrochloride | 2438900-70-8 | 99.3% | 599.16 g/mol | C31H43ClN6O4 | 1 ML
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Tandutinib hydrochloride is a small-molecule tyrosine kinase inhibitor selective for FLT3, with additional activity against c-Kit and PDGFR. It is used as a research reagent in biochemical and cell-based assays to probe signaling pathways and assess antiproliferative effects in oncology studies. The compound has defined physicochemical properties and is suitable for preparing stock solutions for in vitro workflows.
- Potent FLT3 inhibition (IC50 ≈ 0.22 μM).
- Also inhibits c-Kit and PDGFR, supporting broader kinase profiling.
- High purity suitable for research applications (>99% by HPLC).
- Suitable for preparing accurate stock solutions for assays (e.g., 10 mM).
- Provided with datasheet information for safe handling and solubility guidance.
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Medchemexpress LLC SB-505124 hydrochloride | 356559-13-2 | 99.3% | 371.86 g/mol | C20H22ClN3O2 | 5 MG
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SB-505124 hydrochloride is the hydrochloride salt of a selective small-molecule inhibitor of TGF-β type I receptors (ALK4, ALK5, ALK7). It is supplied as a solid research reagent with high purity for use in biochemical assays and cellular signaling studies to modulate TGF-β/activin pathways.
- Selective TGF-β type I receptor inhibitor (ALK4, ALK5, ALK7).
- High purity suitable for analytical and research use.
- Hydrochloride salt form, supplied as a solid.
- Available in small pack sizes for assay development.
- Reported IC50 values in the low-nanomolar range for ALK4 and ALK5.
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Sigma Aldrich Fine Chemicals Biosciences (-)-Riboflavin BioReagent, suitable for cell culture, suitable for insect cell culture, >=98% | 83-88-5 | MFCD00005022 | 25G
(-)-Riboflavin BioReagent, suitable for cell culture, suitable for insect cell culture, >=98% | Purity: >=98% | Mol Wt: 376.36 | 83-88-5 | MFCD00005022 | 25G
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eMolecules AstaTech / (S)-(-)-124-BUTANETRIOL / 1g / 449734826 / 56159 / 97.000 / 42890-76-6 / MFCD00063213 / 106.121 / C4H10O3
AstaTech / (S)-(-)-124-BUTANETRIOL / 1g / 449734826 / 56159 / 97.000 / 42890-76-6 / MFCD00063213 / 106.121 / C4H10O3
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Sigma Aldrich Fine Chemicals Biosciences N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid >=93% | 24967-27-9 | MFCD00135810 | 10MG
N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid >=93% | Purity: >=93% | Mol Wt: 291.25 | 24967-27-9 | MFCD00135810 | 10MG
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